Working group workshops

GSCN workshop
New developments in disease modeling and drug discovery

16 & 17 Nov. 2023
LIFE & BRAIN, Bonn, Venusberg-Campus 1, building 76, 53127 Bonn, Germany
V-Hotel, Haager Weg, 53127 Bonn
Full - 230 €, GSCN member - 170 €, Students - 150 €,
GSCN student member - 120 €,
includes workshop, catering, dinner and accomodation

This two-day workshop will bring together experts from stem cell-based disease modeling and drug development and address the latest developments in this rapidly expanding field.
The event will feature expert talks from academia and pharma, moderated discussion rounds and short project vignettes by the workshop participants. 
Topics to be addressed range from biological and infrastructural prerequisites for stem cell-based drug discovery to strategic issues such as proper placement of stem cell tools in the pharmaceutical value chain. 
We expect a focused and highly interactive event on the beautiful Bonn Medical Campus and look forward to your participation!

Speaker list:

plus selected talks and project pitches. If you are interested to present your specific reserach project as a short 5 minute project statement please send us a brief information on the project to

Flyer  here

Register  here

Workshop Program

Thursday, 16 November 2023

until 12:00 individual arrival at LIFE & BRAIN, Bonn, Venusberg-Campus 1, building 76, 53127 Bonn, Germany
12:00 - 12:10 Welcome
Daniel Besser, GSCN / BIH @ Charité & Oliver Brüstle, LIFE&BRAIN GmbH
  I. Biology: Prerequisites for high fidelity hPSC-based drug discovery
12:10 - 12:30 Progress and challenges in neural disease modelling 
Oliver Brüstle, LIFE&BRAIN GmbH
12:30 - 13:00 Standardization & QC: (inter) national approaches for harmonization in iPSC production 
Harald StachelscheidBIH/Charité, Berlin
13:00 - 13:30 Modeling physical forces with iPSCs: Requirements for heart diseases
Karl-Ludwig LaugwitzTU Munich
13:30 - 14:00 Human stem cell-derived dopaminergic neuron and microglia models for phenotypic drug discovery
Johannes WilbertzKsilink Strasbourg
14:00 - 14:45 Lunch break in the LIFE&BRAIN foyer
14:45 - 15:15 iPS cells as important tool to support drug development
Florian Meier, Boehringer Ingelheim
15:15 - 16:30 Short statements by all participants
Selected project vignettes (5 min each, 9 presentations) 
Workshop participants
16:30 - 16:50 Coffee break
  Workshop Discussion Round I
16:50 - 17:15 Cellular requirements for hPSCs and derivatives
Moderators: Karl-Ludwig Laugwitz & Michael Peitz
17:15 - 17:40 Process standardization, scaling  and automation
Moderators: Harald Stachelscheid & Johannes Wilbertz
17:40 - 18:05 Shaping appropriate read-outs
Moderators: Florian Meier & Jutta Meyer
19:30 - 22:00 Joined dinner at "S im Carré" (included)

Friday, 17 November 2023

  II. Strategy: Efficient allocation of hPSC tools in pharmaceutical value chains
09:00 - 09:30 iPSC based models: how to slot them in the drug development process?
Jan Eickhoff, LDC Dortmund
09:30 - 10:00 Small molecule drug discovery using iPS-derived assays: drug repurposing vs. novel compounds
Ole Pless, Fraunhofer ITMP
10:00 - 10:30 Role of iPSC-derived models in preclinical R&D at Bayer AG
Jutta Meyer & Manuel Grundmann, Bayer AG
10:30 - 11:00 Advancing drug discovery through precision medicine using iPSC and transcriptomics data
Sandra Lubitz & Henrik Renner, Evotec AG, Hamburg
11:00 - 11:30 Coffee break
  Workshop Discussion Round II
11:30 - 12:00 Where is the right place of iPSC models in the drug development process?
Moderators: Sandra Lubitz & Ole Pless
12:00 - 12:30 The academia - pharma interface: Financial incentives for early value chain contributions
Moderators: Jan Eickhoff & Karl-Ludwig Laugwitz
  Wrap Up & Quo Vadis
12:30 - 13:00 Compiling the key challenges and requirements identified in the workshop
Oliver Brüstle & Jan Eickhoff
13:00 - 14:00 Lunch in the LIFE&BRAIN foyer & departure
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